The mysterious second Steve Rogers has
rescued a woman from attack by three villains (last issue); she is
seriously injured but does not want help. Instead she asks Steve how
he got there; Steve is unsure but feels there is someplace that needs
him....
Star-Lord (with Rocket and Groot) is
trying to persuade some aliens to come to the aid of the Earth heroes
stranded in space; instead they shoot at him and he reports his
failure to Captain Marvel. The situation outside the shield is
critical and the only person powerful enough to save the day, Quasar,
is in a coma....
Boomerang, a mobster in Newark, New
Jersey, sets up a meeting between Black Widow and Maria Hill. After
some verbal sparring, Hill hands over a copy of Captain America's
social calendar, listing opportunities for an assassination attempt.
Back at her base she is trying to train the young heroes in her Red
Room to be able to make impossible choices in a split second....
In Montana, Sam Wilson refuses to help
Ant-Man and his team to escape over the Canadian border; they
finally convince him that finding the last fragments of the Cosmic
Cube is the only way to save Steve Cap and return the world to what
it was....
In Washington, Cap is attending a Hydra
Science Fair, still trying to persuade Sharon Carter to join Hydra
when he is called away. A team led by Baron Zemo is in an Atlantean
temple, searching for one of the fragments of the Cosmic Cube.
Finding one they realize it is a fake planted by Namor as a decoy.
Cap orders the temple blown up as a warning to his former ally....
In a mysterious location, a curiously disfigured
Hank Pym awaits the arrival of his “family”....
Steve Rogers puts the injured woman
down beside a stream and with her dying breath she assures Steve that
he will make it home....
In Newark, a bomb explodes in
Boomerang's apartment and he has an unwelcome visitor wanting to know
what passed between Maria Hill and Black Widow—the Hydra
Punisher....
RobFJ with tie-ins related to this issue:-
All-New Guardians Of The Galaxy Annual #1
The GotG fail to recruit any help from alien races and with help from Mantis and Yondu Udonta go looking for a cosmic artefact that turns out to be broken.
Secret Empire Uprising #1
After this issue Black Widow sends Amadeus Cho and Nadia Pym to a try-out for Hydra's youth choir, expecting them to get a chance to assassinate Hydra-Cap. But the Champions' foes the Freelancers will recognise Cho so the rest of the team break in with an image inducer for him. Unfortunately this blows Wasp's cover so she has to flee with them.
CA: Sam Wilson #23
This issue links SE#3 and #4 by showing how Sam Wilson smuggles the Avengers to Canada and gets them a plane to take them further. But unfortunately they wreck the escape route on the way.